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Lanqin Xia


Lanqin Xia
Head of the Research Group of Wheat Genome Editing
Center for Crop Genetics and Breeding
Institute of Crop Sciences
No.12 Zhongguancun South Street
Beijing, 100081, China


  • 1997-2000, PhD in Biochemistry and Molecular Biology, Chinese Academy of Agricultural Sciences, Beijing, China
  • 1992-1995, MS in Plant Genetics and Breeding, Chinese Academy of Agricultural Sciences, Beijing, China
  • 1984-1988, BS in Plant Nutrition and Soil Science, Shenyang Agriculture College, Shenyang, China

Working Experience

  • 1/2009-now, Professor, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences
  • 9/2012-12/2012, Lethbridge Research Center, Agriculture and Agri-Food, Canada, Visiting Scientist.
  • 1/2007-6/2008, Crop Genetic Improvement Centre, Rothamsted Research, UK, RI Research Fellow.
  • 2005, Crop Genetic Improvement Centre, Rothamsted Research, UK, Visiting Scientist.
  • 8/2002-10/2003, Botanic Institute, Munich University, Germany, Postdoctoral Research Scientist.

Research Interests

  • CRISPR/Cas mediated genome editing in crop plants, new methodologies and applications in wheat and rice improvement
  • Development of a novel generation of aphid-proof wheat plants through plant-mediated RNA interference

Academic Qualifications

  • Editorial member, aBIOTECH
  • Reviewer for Nature Plant, Molecular Plant, Plant Biotechnology Journal and etc.

Selected Publications (*corresponding authors)

1. Li SY, Li JY, He YB, Xu ML, Zhang JH, Du WM, Zhao YD andXia LQ*. 2019. Precise gene replacement in rice by RNA transcript-templated homologous recombination. Nature Biotechnology, 37 (4): 445–450.
2. Sun YW, Sparks C, Jones HD, Riley M, Francis F, Du WM andXia LQ*. 2019. Silencing an essential gene involved in infestation and digestion in grain aphid through plant-mediated RNA interference generates aphid-resistant wheat plants.Plant Biotechnology Journal,17:https://doi.org/10.1111/pbi.13067
3. Li JY, Luo JM, Xu ML, Li SY, Zhang JH, Li HY, Yan L, Zhao YD andXia LQ *. 2019. Plant genome editing using xCas9 with expanded PAM compatibility.J Genetics and Genome, https://doi.org/10.1016/j.jgg.2019.03.004
5. Li SY, Li JY, Zhang JH, Du WM, Fu JD, Sutar S, Yunde Zhao YD and Xia LQ* .2018. Synthesis-dependent repair of Cpf1-induced double-strand DNA breaks enables targeted gene replacement in rice. J Exp Bot, 69(20): 4715-4721.
6. Li JY, Zhang X, Sun Y, Zhang J, Du W, Guo X, Li S, Zhao Y, Xia LQ*. 2018. Efficient allelic replacement in rice by gene editing: a case study of the NRT1.1B gene. J of Integr Plant Biology, 60(7): 536-540.
7. Li JY, Sun, Y., Du, J., Zhao, Y., and Xia LQ *. 2017. Generation of targeted point mutations in rice by a modified CRISPR/Cas9 system. Molecular Plant, 10: 526-529.
8. SunYW, Jiao, G., Liu, Z., Zhang, X., Li, J., Guo, X., Du, W., Du, J., Francis, F., Zhao, Y., and Xia LQ*. 2017. Generation of high-amylose rice through CRISPR/Cas9-mediated targeted mutagenesis of starch branching enzymes. Front. Plant Sci, 8, 298.
9. Sun YW, Zhang X, Wu C, He Y, Ma Y, Hou H, Guo X, Du W, Zhao Y, Xia LQ*.2016. Engineering herbicide-resistant rice plants through CRISPR/Cas9-Mediated homologous recombination of acetolactate synthase. Molecular Plant, 9, 628-631.
10. Sun YW, Li JY, and Xia LQ*. 2016. Precise genome modification via sequence-specific nucleases-mediated gene targeting for crop improvement. Front. Plant Sci, 7: 1928.
11. Wang GP, Yu XD, Sun YW, Jones HD, and Xia LQ*. 2016. Generation of Marker- and/or Backbone-Free Transgenic Wheat Plants via Agrobacterium-Mediated Transformation. Front Plant Sci, 7:1324.
12. Yu XD, Liu Z.C., Huang S.L., Chen, Z.Q., Sun, Y., Duan, P.F., Ma, Y.Z., and Xia LQ*. 2016. RNAi-mediated plant protection against aphids. Pest Manag. Sci., 72:1090-1098.
13. Yan T, Chen H, Sun Y., Yu X., and Xia LQ*. 2016. RNA Interference of the Ecdysone Receptor Genes EcR and USP in Grain Aphid (Sitobion avenae F.)Affects Its Survival and Fecundity upon Feeding on Wheat Plants. International Journal of Molecular Sciences, 17:2098.
14. Zhang Y, Li ZX, Yu XD, Fan J, Pickett JA, Jones HD, Zhou JJ, Birkett MA, Caulfield J, Napier JA, Zhao GY, Cheng XG, Shi Y, Bruce T and Xia LQ*. 2015. Molecular characterization of two isoforms of a farnesyl pyrophosphate synthase gene in wheat and their roles in sesquiterpene synthesis and inducible defence against aphid infestation. New Phytologist, 206:1101-1115.
15. Wang GP, Yu XD, Fan J, Wang CS, Xia LQ*. 2015. Expressing an (E)-β-Farnesene synthase in the chloroplast of tobacco affects the preference of green peach aphid and its parasitoid. J of Integr Plant Biology, 2015, 57(9):770-782.
16. Wang DH, Liu Q, Li X, Sun YW, Wang H and Xia LQ*. 2015. Double stranded RNA in the biological control of grain aphid (Sitobion avenae F.). Funct Integr Genomics, 15:211-223.

Members of Research Group